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Trialtrove Analyst
California, USA
+10 year(s) experience
Citeline
While AIDS therapy was once confined to palliative care, clinical progress in the wake of the landmark 1987 approval of zidovudine has seen HIV demoted to a chronic but manageable infection. Following the initial fledgling steps and missteps, the mid-1990s saw the introduction of the now-familiar three-drug combination regimens that raised expectations for a pharmaceutical solution to the epidemic.
Topic Infectious diseases
Trialtrove
Sepsis is a life-threatening illness culminating in multi-organ dysfunction paired with a systemic inflammatory response. The disease burden is considerable: it is the single most expensive condition treated in hospitals, with annual costs in the US projected at nearly $24bn.
Trialtrove
As Zika-related brain abnormalities resulting from congenital infection continue to claim center stage, there has been less fanfare drawn to other viral infections competing for resources in pharmaceutical development.
Topic Clinical trials blog
