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4 Total results for product and free and sample content found

Datamonitor Healthcare

Disappointing Translarna failure is an isolated event for CF pipeline

PTC Therapeutics announced the failure of its ACT CF trial of Translarna (ataluren) in nonsense mutation cystic fibrosis (nmCF) patients, bringing a halt to any further planned developmental activities in the indication. Although there was a slight treatment effect, Translarna failed to significantly improve pulmonary measures compared to placebo.

Topic Comment wire

Datamonitor Healthcare

Pfizer suspends the development of bococizumab

Pfizer has suspended the global development of its pipeline proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, bococizumab, due to a lack of predicted value.

Topic Drug approval Comment wire

Datamonitor Healthcare

Newly approved and late-phase biologics and eosinophilic asthma

Newly approved and late-phase biologics and eosinophilic asthma

Data presented at ATS 2016 support the use of biologics in severe refractory eosinophilic asthma, and will inform the stringent formulary access policies expected to be implemented by payers for these high-cost therapies.

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