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14 Total results for product and free and sample content found

Datamonitor Healthcare

Pulmonary hypertension research wire

Pulmonary hypertension research wire

New clinical data and a deepening treatment algorithm will drive market growth

Topic Research wire

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Datamonitor Healthcare

Chronic Lymphocytic Leukemia

While Rituxan-based therapies remain dominant in the first-line treatment setting for early- and late-stage chronic lymphocytic leukemia (CLL), the majority of patients with relapsed or refractory disease receive Imbruvica. 

Topic Research wire

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Datamonitor Healthcare

Praluent US sales block gives advantage to Amgen's Repatha in dyslipidemia

On 5 January, Amgen secured a court ruling blocking Praluent (alirocumab; Sanofi/Regeneron) from being sold in the US. This ruling clears the way for Amgen’s Repatha (evolocumab) to potentially become the sole proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor in the US market.

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Datamonitor Healthcare

Despite the failure of solanezumab’s EXPEDITION 3 trial, hope for the amyloid hypothesis lingers on

At the 2016 Clinical Trials on Alzheimer’s Disease (CTAD) meeting, Eli Lilly provided a more detailed explanation for the failure of solanezumab in its pivotal EXPEDITION 3 study in mild Alzheimer’s disease.

Topic Research wire Alzheimers

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Datamonitor Healthcare

AHA 2016: Type 2 diabetes treatment is shifting towards therapies with cardiovascular benefits

Controversies to Consensus session at the 2016 American Heart Association (AHA) Scientific Sessions in New Orleans discussed how recent results from cardiovascular outcomes trials should affect current treatment and regulatory practices.

Topic Research wire

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Datamonitor Healthcare

AHA 2016: Interim Data from ORION-1 Trial Encourage Further Development of Inclisiran

Inclisiran offers patients a more convenient dosing schedule that may allow it to compete with marketed PCSK9 inhibitors when approved.

Topic Research wire

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Datamonitor Healthcare

AHA 2016: EFFECT-HF supports use of iron deficiency as an independent therapeutic target in heart failure

Topline results from the Phase III EFFECT-HF study of Injectafer (ferric carboxymaltose; Genesis Pharma/The Galenica Group/Zeria) and its impact on exercise capacity in chronic heart failure patients with iron deficiency were presented at the 2016 American Heart Association (AHA) Scientific Sessions in New Orleans.

Topic Research wire

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Datamonitor Healthcare

AHA 2016: PIONEER-AF trial results will have minimal effect on Xarelto uptake

Reduced doses of Xarelto were shown to lower the rate of bleeding in the PIONEER-AF trial. However, questions still remain as to how efficacious the smaller doses of Xarelto tested in the trial are at protecting against stroke.

Topic Research wire

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Datamonitor Healthcare

AHA 2016: Repatha causes atherosclerotic plaque regression, even at very low LDL-C levels

The Phase III GLAGOV trial showed Repatha (evolocumab; Amgen/Astellas) treatment to reduce atherosclerotic plaque burden in an apparently dose-dependent manner, even at very small low-density lipoprotein-cholesterol (LDL-C) levels.

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