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Roche's blockbuster cancer drug Avastin (bevacizumab) generated nearly $7bn in revenues in 2018, but Avastin's solid status on Roche's top line will be tested with the launch of the first biosimilar in the US. Allergan PLC and Amgen Inc. launched the first US biosimilar for Avastin and Roche's Herceptin (trastuzumab) on 18 July, marking the first oncology biosimilar launches in the US.
It's unclear how the commercial dynamics will play out, but Scrip looked at the commercial and development history of Avastin since its first US FDA approval in 2004 for metastatic colon cancer. Avastin was a blockbuster in its first full year on the market. It rose to become Roche's top-selling drug in 2009 before losing that status in 2012 after a breast cancer indication was withdrawn.
Scrip: industry news and insights
By Sten Stovall
VC Firm Sofinnova’s Chair Papiernik Speaks After New Fund Launch The chairman of Sofinnova Partners told Scrip his newly launched biotech start-up fund aims to profit from Europe’s top science, relatively realistic asset prices, and geopolitical position between the US and China.
Topics Business strategies Drug review
Scrip: industry news and insights
By Kevin Grogan
Ketamine-Like Antidepressant Backed By CHMP If the nasal spray is approved by the European Commission, seven months after getting the green light in the US, Spravato will offer the first new mechanism of action in 30 years to treat major depressive disorder.
Scrip: industry news and insights
By Kevin Grogan 23 Oct 2019
Scrip's Kevin Grogan and Andrew McConaghie's try out the padded cell/recording studio at Informa HQ in London, giving their take...
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