Datamonitor Healthcare has identified the following key highlights from the 50th American Society of Clinical Oncology (ASCO) Annual Meeting, which was held between 30 May and 3 June 2014:

Results from early-phase clinical trials of AstraZeneca’s AZD9291 and Clovis Oncology’s CO-1686 demonstrate strong efficacy of both drugs in relapsed/refractory non-small cell lung cancer (NSCLC) patients with T790M mutations.

Programmed death 1-targeted immunotherapies were a key highlight of ASCO 2014.

Imbruvica’s (ibrutinib; Pharmacyclics/Janssen Biotech) Phase III RESONATE results confirm its strong efficacy as a single agent for the treatment of chronic lymphocytic leukemia (CLL).

Phase II data demonstrate Amgen’s novel antibody therapy blinatumomab is highly effective as a treatment for Philadelphia chromosome (Ph)-negative relapsed/refractory B-precursor acute lymphoblastic leukemia (ALL).

Results from the Phase II ROMULUS trial showed that when combined with Rituxan (rituximab; Roche), Roche’s investigational antibody-drug conjugates polatuzumab vedotin (PoV) and pinatuzumab vedotin (PiV) are clinically active and well tolerated in relapsed/refractory follicular lymphoma (FL) and relapsed/refractory diffuse large B-cell lymphoma (DLBCL) patients.

Highlights from the ASCO 2014 Conference review include:

Results from early-phase clinical trials of AstraZeneca’s AZD9291

Imbruvica's (Ibrutinib; Pharmacyclics/Janssen Biotech) Phase III RESONATE results

Results from the Phase II ROMULUS trial

Download whitepaper

Next steps

Request a Demo

Getting a demo tailored to your needs is the best way to see how our solutions will help you gain an advantage.

Request live demo now:

Request a free demo

Speak to Sales

Our team is ready to hear from you for a particular request or area of interest. Please do not hesitate to reach out and discuss.

Contact Sales

Client Services

US Toll-Free : +1 888 670 8900
US Toll : +1 212-600-3520
UK & Europe : +44 (0) 208 052 0700

Contact Customer Services

Pharma Report Store

Have an immediate and specific information need?

Browse and buy from 1000s of analysis and research reports now:

Shop now

ASCO 2014 Conference Review

Highlights from the ASCO 2014 Conference review include:

Next steps