skip to main content
Close Icon We use cookies to improve your website experience.  To learn about our use of cookies and how you can manage your cookie settings, please see our Cookie Policy.  By continuing to use the website, you consent to our use of cookies.
Global Search Configuration

Market Challenge
Common barriers to success for clinical trials
Traditional approaches to identify qualified sites and investigators (and ultimately recruit patients)may not be sufficient for several reasons:

  • Traditional methods do not support efficient and effective communication and collaboration between CROs, Pharma companies, and clinical trial investigators
  • Traditional data sources do not provide a comprehensive view of all qualified/motivated investigators –i.e., investigators who may not be large/established players in the space
  • Market saturation from top performing research investigators within crowded indications and Therapeutic Areas 


 Having access to these “untapped” sites/investigators is critical when CROs/Pharma companies are facing a market-saturated, competitive landscape and expedited timelines.



Study Profile
Adult Atopic Dermatitis (AD) Phase III Study 
A Top 5 CRO client proactively identified potential risks in the US as it approached the end of the site identification process:

  • It was the fourth study in a program of studies; sites were already saturated and had a decline rate in the US of 1:1
  • Competing study rejections due to other studies in the portfolio and other studies in AD
  • The unique need to identify novel investigators not supporting an earlier study in this AD program (site competition being a key factor in the ability to meet the targeted number of sites)

  To ensure the study met the targeted enrollment period, the Top 5 CRO client set out to create a risk mitigation strategy by building a buffer of approximately 15 additional sites in the US.



The Solution
Citeline Engage: Recruit

  • Recruit in less time using expanded options specific to your study goals 
  • Work with a Citeline Engage study coordinator to create and execute a targeted outreach program to recruit the investigators, physicians, and patients best suited to your unique trial needs. 
  • Recruit acts as your right hand to ensure your trial’s success and maximize ROI.

By using Citeline Engage: Recruit, Pharma Intelligence and the Top 5 CRO client engaged potential, yet-untapped investigators with prior experience in running adult Atopic Dermatitis (AD) trials, as well as new up-andcoming physicians who had significant experience with patients suffering from AD.



Traditional Approach v. Citeline Engage Timelines





Summary: 4 months of recruitment using internal time and resources yielded 54 sites by the target start date (approx. 60% of original desired volume and 70% of adjusted volume).

The Result: Citeline Engage: Recruit delivered 26 new sites – 50% of the volume of traditional methods, in just over 10% of the time.



Citeline Engage: Recruit
Partnering for success

  • Using traditional methods, ~200 sites were contacted and ~70 sites were proposed for the study. After site pre-qualification, 54 sites were proposed to the Sponsor for preselection visits (PSVs).
  • Top 5 CRO client mitigated risk and identified untapped opportunities by going outside of  traditional methods, using Citeline Engage for additional site identification and pre-qualification.
  • Using Citeline Engage: Recruit, within only two weeks we were able to identify an additional 26 investigators with interest in running the trial. This was nearly 50% of the volume using traditional methods, in just ~10% of the time
  • In the end, out of the 26 sites proposed, 10 were approved for a pre-selection visit by the Sponsor.

Next steps

Getting a demo tailored to your needs is the best way to see how our solutions will help you gain an advantage.

Request live demo now:

Our team is always happy to hear from you. Please call us at:

  • US Toll-Free  : +1 888 670 8900
  • US Toll           : +1 908 547 2200
  • UK & Europe : +44 (20) 337 73737
  • Australia        : +61 2 8705 6907
  • Japan              : +81 3 6273 4260

Or please submit your inquiry via the form so that we can provide you the best possible customer service.

Have an immediate and specific information need?

Browse and buy from 1000s of analysis and research reports now: