Is Achieving Trial Success a Roll of the Dice?

06 Jan 2014 by Sylvia Marecki

Topics: Clinical trial optimization |

Provided by Trialtrove: gold standard clinical trials intelligence |

Although many studies have evaluated overall drug development success rates, predominantly by assessing therapeutics’ phase transition rates and probabilities of approval, none have reported trial-level success rates to date. Here, we delve into this area to take a closer look at trial-level success with an eye toward identifying strategies that may correlate with success.

Highlights in this white paper include:

Drug development is a risky endeavor, so just what are the odds of running a successful trial? Many studies have evaluated overall drug
development success rates, predominantly by assessing therapeutics’ phase transition rates and probabilities of approval, yet none have reported trial-level success rates to date. We delve into this question of trial-level success to identify strategies that may correlate with success.

The number of industry-sponsored trials over a five-year period, and the percentage of
completed trials that were deemed positive or successful
The top ten most successful trials by disease, sponsor, drug and trial location
A look at trial success by therapeutic area and sponsor
The countries that hosting the most successful trial activity by therapeutic area
Why more insight into successful clinical trial strategies could help drive the chances of trial success