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The promises of gene therapy are taking a long time to be fulfilled, in part due to challenges in developing gene vectors capable of safe and efficient delivery of therapeutic genes (transgenes) into patients’ cells. Nonetheless, these challenges are being addressed in innovative ways. A variety of first-generation vectors, both viral and non-viral, have been employed in clinical trials with varying degrees of success, and the experience gained is guiding the design of next-generation vectors.

Listen to Speaker: Patricia Reilly, Vice President, Intelligence Alliances and Product Unification, explore and examine:

  • What diseases are gene therapy companies targeting?
  • Volume of clinical trials in recent years
  • Volume of gene therapy companies in recent years
  • As deal volume for partnerships between biotechs and big pharma has increased, has deal value decreased?
  • University deals and spin outs
  • Biotechs with unpartnered therapies- who are they and what are they working on?
  • Acquisitions – Volume and what deal values have increased
  • At what point in the biotechs’ life?
  • What factors may contribute to the escalating cost of acquisition?

Will reimbursement prove to be the biggest barrier as three gene therapies gain regulatory approval?


Learn more in the "Trends in Gene Therapy report", available to buy here

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